| Linux | Windows | Mac | Playlist | XML API | Localplay | Notes | |
|---|---|---|---|---|---|---|---|
| WinAMP | Wine | Yes | Yes | Yes | No | Yes 1) | |
| VideoLAN Client (VLC) | Yes | Yes | Yes | Yes | No | Yes | |
| Amarok | Yes | Yes | Yes | Yes | Yes | No | for LocalPlay: Ampache 3.5+, Amarok 2.1+ |
| quickplay | Yes | Yes | Yes | No | Yes | No | |
| Standard Interface | Yes | Yes | Yes | N/A | N/A | N/A | |
| Coherence DLNA/UPNP MediaServer | Yes | Yes | Yes | N/A | Yes | No | |
| Amdroid | N/A | N/A | N/A | N/A | Yes | No | Official Android Client |
| Ampache Mobile | N/A | N/A | N/A | N/A | Yes | No | 3rd Party PalmPre Client |
| iAmpache client | N/A | N/A | N/A | N/A | Yes | No | Official Iphone Client |